Research Project

The research project titled “Acute effect of creatine and ribose supplementation on oxidative stress indexes and maintaining performance after repeated intensive exercise in elite wrestlers” was compiled in SSRI by Dr. Khosro Ebrahim, faculty member of Shahid Beheshti University as executor. The aim of the project was to investigate the effect of ribose  and creatine acute supplementation on oxidative stress indexes and maintenance of performance ( peak power, mean power, fatigue index ) after repeated intensive exercise in elite wrestlers.

To know a summary of the project it is recommended to read more below:

10 subjects with mean age(22±3 years ) and BMI (23±2 kg/m2) voluntary  participated in this study. Research was quasi-experimental and was done in double blind design. subjects participating in three session(ribose، creatin and placebo). Each session included 4 stages of intensive exercise with 15 min active rest. Each stage included three lower and upper extremity Wingate test and with alternative pattern with 1 min active rest between each test. First time ribose، creatin and placebo ( 0.1 gr per kg of body weight ) were consumed. Also the second dose of supplementes or placebo was give  after the end of second stage of test and third dose was given after the completion of fourth  stage. Blood sample was taken before and after and one hour after recovery. Data was analyzed with repeated measure ( 3×3 ) and the result showed that ribose supplementation decreased the concentration of MDA significantly after exercise and GSSG is correlated to ribose and creatin supplementation(P<0.05) . Also regarding to observed result, CK, LDH, XO, GSH,TAC and asid lactic  did not correlate to ribose and creatin consumption. The result also showed peak power and mean power is correlated to ribose and creatine supplementation (P<0.05). There was no significant difference between supplements and placebo groups, regarding to the fatigue index (P>0.05). Generally it seems that ribose and cratine acute supplementation have significant effect on som oxidative stress indexes. which can enhance anaerobic performance after repeated intensive activities (such as repeated bout of Wingate tests in this study).